Dr. Jenner’s Experiment

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  “March 28th, 1797, I inoculated this girl and carefully rubbed the variolous matter into two slight incisions made upon the left arm. A little inflammation appeared in the usual manner around the parts where the matter was inserted, but so early as the fifth day it vanished entirely without producing any effect on the system.” —Edward Jenner (1749–1823). “The Three Original Publications on Vaccination Against Smallpox.” Portrait of Edward Jenner, painted by James Northcote in either 1803 or 1823

“My Soul Doth Ache”


“ . . . And still she slept an azure-lidded sleep,
In blanched linen, smooth, and lavender'd, 
While he forth from the closet brought a heap 
Of candied apple, quince, and plum, and gourd;
With jellies soother than the creamy curd,  
And lucent syrops, tinct with cinnamon; 
Manna and dates, in argosy transferr'd 
From Fez; and spiced dainties, every one,
From silken Samarcand to cedar'd Lebanon.

These delicates he heap'd with glowing hand
On golden dishes and in baskets bright
Of wreathed silver: sumptuous they stand
In the retired quiet of the night,
Filling the chilly room with perfume light.—
“And now, my love, my seraph fair, awake!
Thou art my heaven, and I thine eremite:
Open thine eyes, for meek St. Agnes' sake,
Or I shall drowse beside thee, so my soul doth ache. . . “


From “The Eve of St. Agnes” by John Keats, published 1820. Painting by Arthur Hughes, 1856

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